Nova Biomedical Bioprofile Flex Analyzer for Sale

SKU: BLE1800234
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ioProfile is a chemistry/cell viability modular instrument that measures up to 15 key cell culture attributes. By combining as many as five separate instruments into one easy-to-use instrument, BioProfile FLEX simplifies workflow and saves time, labor, and operating cost versus multiple instruments. 

Applications of BioProfile FLEX include:

  •  Monitoring the progress of bioreactor runs
  •  Determining consumption and production of key metabolites
  •  Identification of growth-limiting nutrients
  •  Design of feeding strategies
  •  Calibration of bioreactor probes
  •  Measurement of cellular respiration
  •  Balancing media electrolytes
  •  Control levels of waste product.


  • Sample Analysis Time: 2.5 minutes (Gases only – PO2 + PCO2)4.0 minutes 

(Chemistry/Gas & Osmolality)6.25 minutes 

(All 15 tests) 

  • Operating Temperature Range: 15-30°C (59-86°F) 
  • Operating Relative Humidity Range: 20-85% 
  • Sample Size: 1 mL (for all modules) 
  • Sampling Options: Individual via syringe/cup
  • Automated batch using 20-position sampling tray
  • On-line, automated from up to ten bioreactors 
  • Electrical Requirements: 90-264 VAC, 50 to 60 Hz (Universal Power Supply)
  • System Size: Height: 20 in (50 cm) Width: 26 in (66 cm) Depth: 20 in (50 cm)
  • System Weight: Analyzer: 94 lbs (42.6 kg) without reagents
  • Host Computer Monitor/CPU: 41.5 lbs (18.8 kg) 
  • Safety Certifications: TUV: IEC 61010-1:2001 
  • Quality Systems Certifications: TUV: ISO9001:2000 FDA Registered, OPC Compliant, PAT Compatible, 21 CFR Part 11 Compliant


Chemistry/Gas Module AssayMeasurement Range ResolutionMethod

  • Glucose 0.2–30.0 g/L*0.01g/L Biosensor
  • Lactate 0.2–10.0 g/L*0.01g/L Biosensor
  • Glutamine 0.2–12.0 mmol/L*0.01 mmol/L Biosensor
  • Glutamate 0.2–12.0 mmol/L*0.01 mmol/L Biosensor
  • Ammonium 0.2–25.0 mmol/L0.01 mmol/L Direct ISE
  • pH5.000–8.0000.001 Direct ISE
  • PCO23.0–300.0 mmHg0.1 mmHg Direct ISE
  • PO23.0–800.0 mmHg0.1 mmHg Clarke Electrode
  • Sodium 40–220 mmol/L0.1 mmol/L Direct ISE
  • Potassium 1.0–100.0 mmol/L0.01 mmol/L Direct ISE
  • Calcium 0.10–10.0 mmol/L0.01 mmol/L Direct ISE Calculated Tests:O2 Saturation; CO2 Saturation; Temp. Corrected pH, PCO2, PO2
  • *Ranges Reflect User Selectable 1:2 Dilution
  • Osmolality ModuleAssayMeasurement Range ResolutionMethod
  • Osmolality0–1500 mOsm/kg1 mOsm/kgFreezing PointCell Density/Viability Module AssayMeasurement Range ResolutionMethod
  • Cell Diameter8 – 50 μmN/A Digital Imaging
  • Detectable Density 50,000 – 100,000,000cells/mL**N/A Digital Imaging
  • Viability0 – 100%N/A Digital Imaging Phosphate Module Measurement Range 0.20-10 mmol/L
  • Sample Size 500 µL**Ranges Reflect User Selectable 1:2, 1:4, 1:5, 1:10 Dilution
  • IgG Module Measurement Range: 0.10–10.00 g/L* *Ranges Reflect User Selectable 1:2 Dilution


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